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Single-Cell
Isoform-Resolved
Long-Read Sequencing

Grant

Supporting isoform-focused single-cell research with hands-on technology and scientific partnership.

 

Go beyond gene expression. Resolve full-length transcripts, alternative splicing, and isoform usage at single-cell resolution—insights that short-read approaches cannot fully capture.


Building on ArgenTag’s designation as an Oxford Nanopore Compatible Product, this grant brings together our instrument-free single-cell workflow with Oxford Nanopore sequencing. Designed specifically for long-read error profiles, our smart barcoding technology enables fast and reliable read assignment without requiring an inclusion list or additional short-read sequencing.

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  • We encourage researchers at all career stages to apply.


    Complete the short application form below and include your 500-word project proposal.

     

    For questions about eligibility or submission requirements, please review the official Terms and Conditions or email to welcome@argentag.com.


    The submission window closes Friday, October 30, 2026, at 11:59 PM EST.

  • This grant is intended for research programs where transcript-level variation is central to the biological question.

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    We will prioritize projects in the following areas:

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    • Cancer and Immunology

    • Neuroscience

    • Rare diseases

    • Development

     

    Strong proposals from other fields are welcome if isoform diversity, transcript usage, or alternative splicing are core to the hypothesis.

  • Applications will be evaluated based on:

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    ​Scientific impact and originality
    Does the proposed work address a question that cannot be answered without isoform-resolved, full-length transcript data?

     

    Fit to the technology
    Is single-cell long-read sequencing the right tool for the proposed research, and is the proposed experiment technically sound and feasible?

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    Readiness to execute
    This includes:

    • Experience preparing fresh single-cell suspensions.

    • Access to appropriate long-read sequencing platforms.

    • Adequate funding and infrastructure to complete the broader project.

  • Awardees will receive:

    • Up to four reactions (~40,000 cells) of the ArgenTag Single-Cell RNA Library Kit for Long-Read Sequencing.

    • Oxford Nanopore Technologies Ligation Sequencing Kit V14 (SQK-LSK114) and R10.4.1 flow cells.

    • Project planning support and a one-hour debrief with ArgenTag’s Scientific Board.

    • Basic bioinformatics analysis, including demultiplexing, barcode/UMI processing, cell calling, quality metrics, and standard visualizations such as UMAP.

  • The ArgenTag Single-Cell RNA Library Kit for Long-Read Sequencing converts mRNA from individual cells into full-length, cell-barcoded cDNA that seamlessly integrates with Oxford Nanopore ligation sequencing workflows.

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    The kit uses a portable microfluidic chip to partition individual cells into microwells, together with mRNA-capture magnetic beads and ArgenTag’s smart barcoding technology.

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    Learn more at argentag.com/single-cell-solutions

  • Read the full terms and conditions at the Official Grant Rules + Terms and Conditions site.

Single-Cell Isoform-Resolved Long-Read Sequencing Grant.

Applications close on Friday, October 30, 2026, at 11:59 PM EST.


Research Area
PromethION line sequencer availability

Please describe:

― The scientific problem and relevant prior work

― The feasibility of the proposed approach

― Why isoform-resolved, single-cell long-read data are essential to your project

― Expected scientific impact

Grant winner

Grant awardees will be announced on ArgenTag’s social media channels and via email on November 16, 2026, at 11:00 AM ET.

Applications close October 30 at 11:59 PM (EST)

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